BDBM50658097 CHEMBL6164872

SMILES CC(C)(C)C(NC(=O)c1ccc(-n2cc(C(=O)O)cn2)nc1)c1ccccc1

InChI Key InChIKey=SNFQSLFMEQNCCC-UHFFFAOYSA-N

Data  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50658097   

TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 31nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5'-GAAGACCT(1meA)GGCGTCC-3'/5'- CTGGGACGCC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 47nMAssay Description:Inhibition of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 5meC DNA as substrate by FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataKd:  226nMAssay Description:Binding affinity to ALKBH2 (56 to 261 residues)(unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of demethylase activity of ALKBH2 (56 to 261 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 1meA dsDNA as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of demethylase activity of FTO (35 to 505 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 6meA dsDNA as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of demethylase activity of ALKBH5 (66 to 292 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 6meA dsDNA as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658097BDBM50658097(CHEMBL6164872)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of demethylase activity of ALKBH3 (70 to 286 residues)(unknown origin) extracted from Escherichia coli BL21 (DE3) using 1meA dsDNA as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed