BDBM50658189 CHEMBL6143348

SMILES CC(=O)NCSC[C@@H]1NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](NC(C)=O)CSCc2cc3cc(c2)CSC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)CSC3

InChI Key InChIKey=ZWZXATGEDHOMHZ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50658189   

TargetTyrosine-protein kinase JAK2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658189BDBM50658189(CHEMBL6143348)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JAK2 (unknown origin) using srctide as substrate preincubated with compound for 1 hr followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658189BDBM50658189(CHEMBL6143348)
Affinity DataKd:  1.30E+5nMAssay Description:Binding affinity to his-tagged JAK2 (826 to 1132 residues) (unknown origin) assessed as dissociation constant incubated for 30 mins by MST analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed