BDBM50658190 CHEMBL6160968

SMILES Cn1nc(-c2ccnn2C)cc1CNC(=O)c1cc(-c2ccco2)ccc1Cl

InChI Key InChIKey=DRUXADDGGKWTSU-UHFFFAOYSA-N

Data  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50658190   

TargetMetabotropic glutamate receptor 1(Mouse)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of mouse mGlu1 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu8 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu2 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu2 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu3 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu5 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu4 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu3 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658190BDBM50658190(CHEMBL6160968)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu8 receptorMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed