BDBM50658231 CHEMBL6144430

SMILES CN(C)C(=O)c1cc2cnc(N[C@H]3CC[C@H](N)CC3)nc2n1C1CCCC1

InChI Key InChIKey=HZJPJDOVXYTUTI-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50658231   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL

LigandBDBM50658231(CHEMBL6144430)Copy SMILESCopy InChI

Affinity DataIC50: 7.70nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using CTD3 peptide as substrate preincubated with compound for 10 mins followed by substrate addition a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPDB

In Depth
Date in BDB:
6/5/2026
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
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TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL

LigandBDBM50658231(CHEMBL6144430)Copy SMILESCopy InChI

Affinity DataIC50: 15nMAssay Description:Inhibition of CDK4/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPDB

In Depth
Date in BDB:
6/5/2026
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Peking University Shenzhen Graduate School

Curated by ChEMBL

LigandBDBM50658231(CHEMBL6144430)Copy SMILESCopy InChI

Affinity DataIC50: 624nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) using FAM-P8 peptide as substrate preincubated with compound for 10 mins followed by substrate addition...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPDB

In Depth
Date in BDB:
6/5/2026
Entry Details
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL