BDBM50658277 CHEMBL6133737

SMILES CC[C@H](C)[C@H]1C(=O)N(C[C@H]2N1C(=O)CCN2C(=O)NCCCC(F)(F)F)Cc3ccc(c4c3cccc4)OC

InChI Key InChIKey=ZCPTWZWAPHZUMM-UHFFFAOYSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50658277   

TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658277BDBM50658277(CHEMBL6133737)
Affinity DataEC50:  330nMAssay Description:Agonist activity at Staphylococcus aureus ClpP extracted from Escherichia coli BL21 (DE3) cells using FITC-casein as substrate assessed as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658277BDBM50658277(CHEMBL6133737)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at Staphylococcus aureus ClpP extracted from Escherichia coli BL21 (DE3) cells using alpha-casein as substrate assessed as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658277BDBM50658277(CHEMBL6133737)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at human ClpP extracted from Escherichia coli Rosetta (DE3) cells using alpha-casein as substrate assessed as substrate hydrolysis p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent Clp protease proteolytic subunit(Escherichia coli (strain K12))
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658277BDBM50658277(CHEMBL6133737)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at Escherichia coli ClpP using alpha-casein as substrate assessed as substrate hydrolysis preincubated for 15 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed