BDBM50658328 CHEMBL6167833

SMILES CC(=O)N1CCC2(CC1)CC(=O)c1ccc(-c3nc(Nc4ccc(N5CCN(C(=O)C6CC6)CC5)cn4)ncc3F)cc1O2

InChI Key InChIKey=SYKRKPBLEITCOH-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50658328   

TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658328BDBM50658328(CHEMBL6167833)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK6 (unknown origin) incubated for 60 mins in presence of ATP by plate reader based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658328BDBM50658328(CHEMBL6167833)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658328BDBM50658328(CHEMBL6167833)
Affinity DataKd:  85nMAssay Description:Binding affinity to full length GFP tagged CDK6/cyclin D3 (unknown origin) overexpressed in HEK293T cells assessed as dissociation constant by MST an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658328BDBM50658328(CHEMBL6167833)
Affinity DataKd:  107nMAssay Description:Binding affinity to full length GFP tagged CDK4/cyclin D3 (unknown origin) overexpressed in HEK293T cells assessed as dissociation constant by MST an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed