BDBM50658357 CHEMBL6133750

SMILES Cn1cnc2ccc(-c3nc4cnc(NC5CC5)nc4n(-c4ccc(OC(F)F)cc4)c3=O)cc21

InChI Key InChIKey=LYFLJEMJXLNQRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50658357   

TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658357BDBM50658357(CHEMBL6133750)
Affinity DataIC50: 49nMAssay Description:Inhibition of MAT2A (unknown origin) using L-methionine and ATP as substrate preincubated with compound for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed