BDBM50658398 CHEMBL6152845

SMILES Cc1cnc(Nc2ccc(S(N)(=O)=O)cc2)nc1Nc1nccs1

InChI Key InChIKey=WRKPIAIMXOPJDB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50658398   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658398BDBM50658398(CHEMBL6152845)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) using lipid substrate incubated for 40 mins in presence of ATP by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658398BDBM50658398(CHEMBL6152845)
Affinity DataIC50: 119nMAssay Description:Inhibition of CDK5/p35 (unknown origin) using lipid substrate incubated for 40 mins in presence of ATP by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658398BDBM50658398(CHEMBL6152845)
Affinity DataIC50: 215nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin) using lipid substrate incubated for 40 mins in presence of ATP by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Southern Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658398BDBM50658398(CHEMBL6152845)
Affinity DataIC50: 942nMAssay Description:Inhibition of CDK4/cyclin D (unknown origin) using lipid substrate incubated for 40 mins in presence of ATP by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed