BDBM50659091 CHEMBL6134055

SMILES COc1cc(-c2ncc(F)c(Nc3ccc4nc(C)cc(N)c4c3)n2)cc(OC)c1OC

InChI Key InChIKey=DJRAKTLQKMVYOK-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50659091   

TargetProtein arginine N-methyltransferase 7(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659091BDBM50659091(CHEMBL6134055)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human PRMT7More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659091BDBM50659091(CHEMBL6134055)
Affinity DataKd:  7.12E+3nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant full length human PRMT7 extracted from baculovirus infected Sf9 cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659091BDBM50659091(CHEMBL6134055)
Affinity DataIC50: 9.91E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human PRMT7 extracted from baculovirus infected Sf9 cells using Histone H4 (1 to 21) peptide as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Ningbo University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659091BDBM50659091(CHEMBL6134055)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PRMT5More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed