BDBM50659396 CHEMBL6134104

SMILES O=C1S/C(=C\c2ccccc2)C(=O)N1CNc1nc(-c2cc(Cl)cs2)c(Nc2ccccc2)s1

InChI Key InChIKey=NSHASKBILXHBTO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50659396   

TargetCholinesterase(Horse)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659396BDBM50659396(CHEMBL6134104)
Affinity DataIC50: 230nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-secretase 1(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659396BDBM50659396(CHEMBL6134104)
Affinity DataIC50: 490nMAssay Description:Inhibition of BACE-1 (unknown origin) 667-676- (2, 4-dinitrophenyl) Lys-Arg-Arg amide trifluoroacetate as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659396BDBM50659396(CHEMBL6134104)
Affinity DataIC50: 610nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate and in presence of TMPD preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659396BDBM50659396(CHEMBL6134104)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human MAO-A using tyramine/benzylamine as substrate measured after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659396BDBM50659396(CHEMBL6134104)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of 5-LOX (unknown origin) using linoleic acid as substrate incubated for 5 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed