BDBM50659604 CHEMBL6142486

SMILES O=c1[nH]c2c(c(=O)n1Cc1ccc(C(F)(F)F)cc1)CN(Cc1cccc([N+](=O)[O-])c1)CC2

InChI Key InChIKey=PNWFKFMFPUOMLB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50659604   

TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659604BDBM50659604(CHEMBL6142486)
Affinity DataEC50:  2.88E+3nMAssay Description:Activation of human ClpP using FITC-casein as substrate assessed as increase in proteolytic activity preincubated for 15 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659604BDBM50659604(CHEMBL6142486)
Affinity DataKi:  2.67E+4nMAssay Description:Displacement of [3H]-N-methylspiperone from human D3 receptor extracted from HEK293 cell membrane assessed as inhibition constant incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659604BDBM50659604(CHEMBL6142486)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-N-methylspiperone from human D2L receptor extracted from HEK293 cell membrane assessed as inhibition constant incubated for 60 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed