BDBM50659787 CHEMBL6147310

SMILES C[C@H]1CC[C@@H](N(C1)C(=O)C(=O)Nc2cc(c(nc2)N)C3CC3)c4ccc5c(c4)ncs5

InChI Key InChIKey=QNHCUYXLHQODAB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659787   

TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659787BDBM50659787(CHEMBL6147310)
Affinity DataIC50: 5nMAssay Description:Inhibition of PRMT5 in MTAP-null human HAP1 cells assessed as decrease in SDMA level incubated for 24 hrs by ICW assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)