BDBM50659832 CHEMBL6149904

SMILES COc1ncc(NC(=O)C(=O)N2C[C@@H](C)N(C(=O)C3(C)CC3)C[C@@H]2c2ccc(F)cc2)cc1C(N)=O

InChI Key InChIKey=FQMOLGRALVDUQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659832   

TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659832BDBM50659832(CHEMBL6149904)
Affinity DataIC50: 8nMAssay Description:Inhibition of PRMT5 in MTAP-null human HAP1 cells assessed as decrease in SDMA level incubated for 24 hrs by ICW assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed