BDBM50660068 CHEMBL6160306

SMILES CN(C(=O)NCC(F)(F)Cl)[C@H]1CCCCc2cnccc21

InChI Key InChIKey=PFBZDLXXZIZCFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50660068   

TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660068BDBM50660068(CHEMBL6160306)
Affinity DataIC50: 158nMAssay Description:Inhibition of human SARM1 extracted from HEK293 cell lysate in presence of NAD by biochemical (Fluorescence Readout) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNAD(+) hydrolase SARM1(Human)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660068BDBM50660068(CHEMBL6160306)
Affinity DataIC50: 218nMAssay Description:Inhibition of human SARM1 expressed in human SH-SY5Y cells assessed as SARM1 P1a activity measured after 60 mins by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed