BDBM50660167 CHEMBL6161830

SMILES CNC(=O)c1cnc2cc1Nc1cc(cc(-c3ccn(C)n3)c1OC)CCOCc1cccc(n1)N2

InChI Key InChIKey=XRANKYHFKDBBKP-UHFFFAOYSA-N

Data  1 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50660167   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
South China University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660167BDBM50660167(CHEMBL6161830)
Affinity DataIC50: 1nMAssay Description:Inhibition of TYK2 JH2 pseudokinase domain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
South China University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660167BDBM50660167(CHEMBL6161830)
Affinity DataKd: >10nMAssay Description:Binding affinity to JAK1 JH1 pseudokinase domain (unknown origin) assessed as dissociation constant by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
South China University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660167BDBM50660167(CHEMBL6161830)
Affinity DataKd: >10nMAssay Description:Binding affinity to TYK2 JH1 pseudokinase domain (unknown origin) assessed as dissociation constant by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
South China University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660167BDBM50660167(CHEMBL6161830)
Affinity DataKd: >10nMAssay Description:Binding affinity to JAK3 JH1 pseudokinase domain (unknown origin) assessed as dissociation constant by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
South China University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660167BDBM50660167(CHEMBL6161830)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to JAK2 JH1 pseudokinase domain (unknown origin) assessed as dissociation constant by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed