BDBM50660183 CHEMBL6172228

SMILES C=CC(=O)C1CCC[C@@H](n2nc(-c3ccc4ccccc4c3)c3c(N)ncnc32)C1

InChI Key InChIKey=QTLHMAIRZCHDPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50660183   

TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660183BDBM50660183(CHEMBL6172228)
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660183BDBM50660183(CHEMBL6172228)
Affinity DataIC50: 88nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed