BDBM50660326 CHEMBL6150561

SMILES Cc1ccccc1NC(=O)C(C)n1nc(C(=O)Nc2ccccc2)c2ccccc21

InChI Key InChIKey=BHDVEYOSQMNXPF-UHFFFAOYSA-N

Data  12 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50660326   

TargetSolute carrier organic anion transporter family member 2B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 170nMAssay Description:Inhibition of OATP2B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of pyranine uptake preincubated for 5 mins followed by...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1A2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 710nMAssay Description:Inhibition of OATP1A2 (unknown origin) transfected in human A-431 cells assessed as inhibition of SR101 uptake preincubated for 5 mins followed by SR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1B3(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 788nMAssay Description:Inhibition of OATP1B3 (unknown origin) transfected in human A-431 cells assessed as inhibition of DHPDS uptake preincubated for 5 mins followed by DH...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in calcein-AM fluorescence intensity using calcein-AM as tracer preincubated for 30...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells assessed as increase in rhodamine123 fluorescence intensity using rhodamine123 as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataEC50:  3.89E+3nMAssay Description:Reversal of ABCB1-mediated multidrug resistance in human A2780 ADR cells assessed as increase in doxorubicin-mediated cytotoxicity incubated for 72 h...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of ABCB1 in human A2780 ADR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMonocarboxylate transporter 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of MCT-1 in human A549 cells assessed as potentiation of 3-BP-mediated cytotoxicity by measuring decrease in cell viability incubated for ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 1B1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of OATP1B1 (unknown origin) transfected in human A-431 cells assessed as inhibition of DHPDS uptake preincubated for 5 mins followed by DH...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of ABCC1 in human NCI-H69AR cells assessed as increase in daunorubicin fluorescence intensity using daunorubicin as tracer preincubated fo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataEC50:  1.34E+4nMAssay Description:Reversal of ABCC1-mediated multidrug resistance in human NCI-H69AR cells assessed as increase in doxorubicin-mediated cytotoxicity incubated for 72 h...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in pheophorbide A fluorescence intensity using pheophor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in dog MDCK-II-BCRP cells assessed as increase in Hoechst 33342 fluorescence intensity using Hoechst 3...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier family 22 member 2(Human)
University of Lubeck and University Medical Center Schleswig-Holstein

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660326BDBM50660326(CHEMBL6150561)
Affinity DataIC50: 5.13E+4nMAssay Description:Inhibition of OCT2 (unknown origin) expressed in HEK293 cells assessed as inhibition of ASP+ uptake incubated for 5 mins by fluorescence based analys...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed