BDBM50661100 CHEMBL6132636

SMILES COc1cc(-c2nc(Nc3ccc4nc(C)cc(N)c4c3)c3sccc3n2)cc(OC)c1OC

InChI Key InChIKey=XVEDBNJFEXTJBL-UHFFFAOYSA-N

Data  7 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50661100   

TargetProtein arginine N-methyltransferase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataKd:  320nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant full length human PRMT7 extracted from baculovirus infected Sf9 cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human PRMT7 extracted from baculovirus infected Sf9 cells using Histone H4 (1 to 21) peptide as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full length human PRMT1 extracted from baculovirus expression system preincubated for 10 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged human PRMT8 (61 to 394 residues) extracted from Escherichia coli preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT6 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 3 hrs by MTase-Glo detection reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full length human PRMT4 extracted from baculovirus expression system preincubated for 10 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PRMT3 (2 to 531 residues) extracted from Escherichia coli preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661100BDBM50661100(CHEMBL6132636)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT9 (unknown origin) incubated overnight by Alphascreen microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed