BDBM50661340 CHEMBL6168703

SMILES Cc1cc(F)ccc1Oc1ncc(C(F)(F)F)cc1C(=O)Nc1cccc([S@](C)(=N)=O)c1

InChI Key InChIKey=IIJWTXGHWFZLBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50661340   

TargetSodium channel protein type 10 subunit alpha(Human)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661340BDBM50661340(CHEMBL6168703)
Affinity DataIC50: 35nMAssay Description:Inhibition of human Nav1.8 with resting membrane potential at half inactivated state by PatchXpress high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661340BDBM50661340(CHEMBL6168703)
Affinity DataIC50: 53nMAssay Description:Inhibition of human Nav1.8 with resting membrane potential by PatchXpress high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Mouse)
Lieber Institute for Brain Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661340BDBM50661340(CHEMBL6168703)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of mouse Nav1.8 with resting membrane potential at half inactivated state by PatchXpress high-throughput electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed