BDBM50661449 CHEMBL1572273

SMILES O=C1C(Cl)=C(Nc2ccccc2)C(=O)N1c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JEQXBHICYNONBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50661449   

TargetRNA demethylase ALKBH5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661449BDBM50661449(CHEMBL1572273)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of ALKBH5 (unknown origin) using 5'-ATTGTCA(m6A)CAGCAGA-FAM-3' as substrate measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661449BDBM50661449(CHEMBL1572273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ALKBH5 (unknown origin) using 5'-TAGACATTGCCATTCTCGATAGG (m6A) TCCGGTCAAACCTAGAC GAATTCCA-3' as substrate measured after 2 hrs in prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed