BDBM50662110 CHEMBL6169357

SMILES Nc1ccc2cc(C(=O)N(Cc3ccc(Br)cc3)Cc3ccccc3F)ccc2n1

InChI Key InChIKey=CDVCMTFZXUCHLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662110   

LigandChemical structure of BindingDB Monomer ID 50662110BDBM50662110(CHEMBL6169357)
Affinity DataIC50: 60nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2A as substrate preincubated for 1 hr in presence of SAM/MTA followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50662110BDBM50662110(CHEMBL6169357)
Affinity DataIC50: 750nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2A as substrate preincubated for 1 hr in presence of SAM followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed