BDBM50662114 CHEMBL6134709

SMILES Cc1cc(N)nc2ccc(C(=O)N(Cc3ccc(C(F)(F)F)cn3)CC(C)C)cc12

InChI Key InChIKey=OHYNTMOKPDTVSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662114   

LigandChemical structure of BindingDB Monomer ID 50662114BDBM50662114(CHEMBL6134709)
Affinity DataIC50: 35nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2A as substrate preincubated for 1 hr in presence of SAM/MTA followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50662114BDBM50662114(CHEMBL6134709)
Affinity DataIC50: 76nMAssay Description:Inhibition of human PRMT5/MEP50 using Histone H2A as substrate preincubated for 1 hr in presence of SAM followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed