BDBM50662115 CHEMBL6170291

SMILES Cn1cc2cc(-c3ccc4nc([C@H](O)C5CC(F)(F)C5)sc4n3)cnc2n1

InChI Key InChIKey=QRGLCFHCLIMZNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662115   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662115BDBM50662115(CHEMBL6170291)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of 15-PGDH in human A549 cells assessed as increase in IL-1beta-stimulated PGE2 levels measured after 24 hrs by competitive HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662115BDBM50662115(CHEMBL6170291)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant human 15-PGDH using PGE2 and beta-NAD+ as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed