BDBM50662116 CHEMBL6173663

SMILES Cn1cc2cc(-c3ccc4cc(C5(O)CC(C)(C)C5)sc4n3)cnc2n1

InChI Key InChIKey=SHEYVMZEMNMTME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662116   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662116BDBM50662116(CHEMBL6173663)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of 15-PGDH in human A549 cells assessed as increase in IL-1beta-stimulated PGE2 levels measured after 24 hrs by competitive HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662116BDBM50662116(CHEMBL6173663)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of recombinant human 15-PGDH using PGE2 and beta-NAD+ as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed