BDBM50662117 CHEMBL6151495

SMILES Cn1cc2cc(-c3ccc4cc([C@]5(O)C[C@@H](C(F)(F)F)C5)sc4n3)cnc2n1

InChI Key InChIKey=CDNMZNAPUCCEIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662117   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662117BDBM50662117(CHEMBL6151495)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of 15-PGDH in human A549 cells assessed as increase in IL-1beta-stimulated PGE2 levels measured after 24 hrs by competitive HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662117BDBM50662117(CHEMBL6151495)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human 15-PGDH using PGE2 and beta-NAD+ as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed