BDBM50662336 CHEMBL6164076

SMILES COc1csc(C(=O)Nc2cccc(NS(C)(=O)=O)c2)c1

InChI Key InChIKey=PECOFTRYKFNRPW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50662336   

TargetATP-dependent RNA helicase A(Human)
Accent Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662336BDBM50662336(CHEMBL6164076)
Affinity DataEC50:  338nMAssay Description:Inhibition of human DHX9 using double-stranded RNA and ATP as substrate pre-incubated for 15 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent RNA helicase A(Human)
Accent Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662336BDBM50662336(CHEMBL6164076)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human DHX9 using split-beacon oligonucleotide and ATP as substrate pre-incubated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetATP-dependent RNA helicase A(Human)
Accent Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662336BDBM50662336(CHEMBL6164076)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of DHX9 in human PBMC assessed as target engagement by measuring circBRIP1 incubated for 24 hrs by Taqman qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed