BDBM50662484 CHEMBL6171361

SMILES Nc1ncc(-c2cccnc2F)cc1C(=O)N[C@H]1CCC[C@@H]1OCc1ccc(-c2ccc3c(c2)CCC[C@@H]3N2CCN(C[C@H](O)CO)CC2)cc1

InChI Key InChIKey=LYOFWWMIRHDSLV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662484   

TargetTyrosine-protein kinase Mer(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662484BDBM50662484(CHEMBL6171361)
Affinity DataEC50:  4nMAssay Description:Inhibition of Myc-tagged/TEL dimerization domain-fused human MerTk kinase domain expressed in mouse BaF3 cells assessed as inhibition of MerTk phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662484BDBM50662484(CHEMBL6171361)
Affinity DataIC50: 521nMAssay Description:Inhibition of TNK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed