BDBM50662579 CHEMBL6147392

SMILES COC(=O)c1csc(CNC(=O)Nc2c(-c3cccc(Cl)c3Cl)ccc3c2CCC3)c1

InChI Key InChIKey=YRWAOKVNHBUYDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50662579   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662579BDBM50662579(CHEMBL6147392)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome pathway in human THP-1 cells assessed as LPS-stimulated IL-1beta release pretreated with LPS for 3 hrs followed by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed