BDBM50662631 CHEMBL6152003

SMILES CS(=O)(=O)c1ccc(-c2nc(C(=O)NCc3cn(-c4cc(NC5CC(F)(F)C5)ccn4)nn3)cs2)cc1

InChI Key InChIKey=AXUQPBASSXNNOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662631   

TargetP2X purinoceptor 7(Mouse)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662631BDBM50662631(CHEMBL6152003)
Affinity DataIC50: 56nMAssay Description:Antagonist activity against mouse P2X7 receptor expressed in ATP-stimulated HEK293 cells assessed as influx of PI by fluorescence dye uptake assay re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662631BDBM50662631(CHEMBL6152003)
Affinity DataIC50: 63nMAssay Description:Antagonist activity against human P2X7 receptor expressed in ATP-stimulated HEK293 cells assessed as influx of PI by fluorescence dye uptake assay re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed