BDBM50662880 CHEMBL6160830

SMILES CN(C)C(=O)Cc1ccc2nc(N3CC(c4cnc(Nc5cnn(C)c5)c(C(N)=O)n4)C3)oc2c1

InChI Key InChIKey=IDWCYXNGJMJMSH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662880   

TargetTyrosine-protein kinase Mer(Human)
AbbVie Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662880BDBM50662880(CHEMBL6160830)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of N-terminal GST-fused recombinant human MER (528 to 999 residues) extracted from baculovirus expression system preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
AbbVie Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662880BDBM50662880(CHEMBL6160830)
Affinity DataEC50:  18nMAssay Description:Inhibition of phosphorylation of Myc-tagged human MerTK expressed in mouse BaF3 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed