BDBM50662888 CHEMBL6162698

SMILES Cn1cc(Nc2ncc(C3CN(c4nc5ccc(OCC(C)(C)O)cc5o4)C3)nc2C(N)=O)cn1

InChI Key InChIKey=RVQUYXMISPBXLS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50662888   

TargetTyrosine-protein kinase Mer(Human)
AbbVie Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662888BDBM50662888(CHEMBL6162698)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal GST-fused recombinant human MER (528 to 999 residues) extracted from baculovirus expression system preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
AbbVie Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662888BDBM50662888(CHEMBL6162698)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of N-terminal his-tagged recombinant human Axl (473 to end residues) extracted from baculovirus infected Sf9 cells preincubated for 30 min...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
AbbVie Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662888BDBM50662888(CHEMBL6162698)
Affinity DataEC50:  6.40nMAssay Description:Inhibition of phosphorylation of Myc-tagged human MerTK expressed in mouse BaF3 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
AbbVie Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662888BDBM50662888(CHEMBL6162698)
Affinity DataIC50: 307nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human Tyro-3 (455 to end residues) extracted from baculovirus infected Sf9 cells preincubated for 30 ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed