BDBM50662889 CHEMBL6171032

SMILES CC(C)(CCOc1ccc2c(c1)oc(n2)N3CC(C3)c4cnc(c(n4)C(=O)N)Nc5cnn(c5)C)O

InChI Key InChIKey=MALAUNPIQXEERD-UHFFFAOYSA-N

Data  3 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50662889   

TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662889BDBM50662889(CHEMBL6171032)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of N-terminal GST-fused recombinant human MER (528 to 999 residues) extracted from baculovirus expression system preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase receptor UFO(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662889BDBM50662889(CHEMBL6171032)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of N-terminal his-tagged recombinant human Axl (473 to end residues) extracted from baculovirus infected Sf9 cells preincubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662889BDBM50662889(CHEMBL6171032)
Affinity DataEC50:  12nMAssay Description:Inhibition of phosphorylation of Myc-tagged human MerTK expressed in mouse BaF3 cells by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase receptor TYRO3(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662889BDBM50662889(CHEMBL6171032)
Affinity DataIC50: 263nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human Tyro-3 (455 to end residues) extracted from baculovirus infected Sf9 cells preincubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed