BDBM50662938 CHEMBL6171670
SMILES O=C(O)c1sc2cc(F)sc2c1Cl
InChI Key InChIKey=UXMBSHHPPVOPJU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50662938
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Ligand InfoPDB
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of BDK in human skeletal myocyte using BCKDHA as substrate assessed as inhibition of substrate phosphorylation incubated for 60 mins by Al...More data for this Ligand-Target Pair
Ligand InfoPDB

3D Structure (crystal)