BDBM50662939 CHEMBL6173779
SMILES CCc1c(F)c(F)cc(-c2c(C(=O)O)sc3cc(F)ccc23)c1F
InChI Key InChIKey=CPOSHNIQLNIWKX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50662939
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Ligand Info
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of BDK in human skeletal myocyte using BCKDHA as substrate assessed as inhibition of substrate phosphorylation incubated for 60 mins by Al...More data for this Ligand-Target Pair
Ligand Info
