BDBM50663185 CHEMBL6169990

SMILES NC(=O)c1nn(-c2ccnc(N[C@H]3CCCN(C(=O)C4CC4)C3)n2)cc1/C=C/c1ccccc1

InChI Key InChIKey=XWMXABITTGTRDD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50663185   

TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663185BDBM50663185(CHEMBL6169990)
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK3 (unknown origin) using 33P-ATP as substrate incubated for 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663185BDBM50663185(CHEMBL6169990)
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK3 (unknown origin) using ATF as substrate in presence of [gamma-33P]ATP incubated for 40 mins by scintillation counter analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Hanyang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663185BDBM50663185(CHEMBL6169990)
Affinity DataIC50: 14nMAssay Description:Inhibition of GSK3beta (unknown origin) using 33P-ATP as substrate incubated for 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Hanyang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663185BDBM50663185(CHEMBL6169990)
Affinity DataIC50: 35nMAssay Description:Inhibition of GSK3alpha (unknown origin) using 33P-ATP as substrate incubated for 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663185BDBM50663185(CHEMBL6169990)
Affinity DataIC50: 80nMAssay Description:Inhibition of JNK1 (unknown origin) using 33P-ATP as substrate incubated for 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663185BDBM50663185(CHEMBL6169990)
Affinity DataIC50: 450nMAssay Description:Inhibition of JNK2 (unknown origin) using 33P-ATP as substrate incubated for 2 hrs by P81 filter-binding methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed