BDBM50663412 CHEMBL6166881

SMILES O=C(Nc1ccc(C2CCC(F)(F)CC2)cc1)Nc1c[nH]c2ccc(Cl)cc12

InChI Key InChIKey=KBADUNGUPYKWOD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50663412   

TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663412BDBM50663412(CHEMBL6166881)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of CMA-induced STING activation in mouse RAW-Dual cellMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663412BDBM50663412(CHEMBL6166881)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of STING in mouse RAW-Dual cells transfected with HT-DNA /2',3'-cGAMP by luciferase based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663412BDBM50663412(CHEMBL6166881)
Affinity DataIC50: 34nMAssay Description:Inhibition of STING in human THP1-Dual cells transfected with HT-DNA /2',3'-cGAMP by luciferase based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclic GMP-AMP synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663412BDBM50663412(CHEMBL6166881)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of cGAS (unknown origin) by pyrophosphatase-coupled assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed