BDBM50663842 CHEMBL6173823

SMILES CC(C)Oc1cc(Nc2ccnc(-c3cnn(S(=O)(=O)C4CC4)c3)n2)ncc1-c1cnn(-c2ccncc2)c1

InChI Key InChIKey=KYQBEVVZKXTVQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50663842   

TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663842BDBM50663842(CHEMBL6173823)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR de119/T790M/C797S mutant (694 to 1022 residues)(unknown origin) using BML-P243 as substrate incubated for 90 mins in presence of A...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co., Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663842BDBM50663842(CHEMBL6173823)
Affinity DataIC50: 237nMAssay Description:Inhibition of N-terminal GST-tagged wild-type human EGFR (669 to 1210 residues) expressed in Sf21 cells using BML-P243 as substrate incubated for 90 ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed