BDBM50663903 CHEMBL6170056

SMILES CC(C)CCN1c2nc(Nc3cc(F)c(O)c(F)c3)ncc2N(C)C(=O)[C@@H]1C

InChI Key InChIKey=DTEKTGDVSARYDS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50663903   

TargetSerine/threonine-protein kinase VRK1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663903BDBM50663903(CHEMBL6170056)
Affinity DataIC50: 112nMAssay Description:Inhibition of VRK1 (3 to 364 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3)-R3 cellsMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase VRK2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663903BDBM50663903(CHEMBL6170056)
Affinity DataIC50: 196nMAssay Description:Inhibition of VRK2 (14 to 335 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3)-R3 cellsMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)