BDBM50664056 CHEMBL6160197

SMILES COc1cc2c(Nc3ccc(Oc4ccccc4F)c(C)c3)ncnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=YKDWSEHZXNNFNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50664056   

TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664056BDBM50664056(CHEMBL6160197)
Affinity DataIC50: 37nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) using poly (Glu:Tyr)(4:1) as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed