BDBM50664131 CHEMBL6151602

SMILES CCC(=O)Nc1ccc(-c2ccccc2N(Cc2cc(Cl)ccc2OCCOC)C(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=XEFQVFYCFUEODO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50664131   

TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664131BDBM50664131(CHEMBL6151602)
Affinity DataIC50: 340nMAssay Description:Inhibition of NLRP3 inflammasome activation in mouse JJ74.A1 cells assessed as reduction in LPS/ATP-induced IL-1 beta release pretreated with LPS for...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664131BDBM50664131(CHEMBL6151602)
Affinity DataKd:  470nMAssay Description:Binding affinity to NLRP3 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed