BDBM50664148 CHEMBL6172941

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@]1(C)CCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O)[C@@H](C)O

InChI Key InChIKey=XDWPFLPGCPKHJE-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50664148   

TargetKRas/Son of Sevenless Homolog 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664148BDBM50664148(CHEMBL6172941)
Affinity DataIC50: 16nMAssay Description:Inhibition of KRAS G12D mutant/SOS1 (unknown origin) interaction by TR-FRET assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEphrin type-B receptor 2(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664148BDBM50664148(CHEMBL6172941)
Affinity DataIC50: 870nMAssay Description:Inhibition of pERK in human ASPC1 cells by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664148BDBM50664148(CHEMBL6172941)
Affinity DataKd:  3.92E+3nMAssay Description:Binding affinity to KRas (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase HRas(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664148BDBM50664148(CHEMBL6172941)
Affinity DataKd:  3.92E+3nMAssay Description:Binding affinity to HRas (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed