BDBM50664272 CHEMBL6165880

SMILES COc1cc(N2CCC(N3CCN(CC4CCN(c5ccc6c(c5)CN(C5CCC(=O)NC5=O)C6=O)CC4)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1

InChI Key InChIKey=VLZMXJWNVDPMPQ-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50664272   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSLC34A2-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ROS1-SLC34A2 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCD74-ROS1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ROS1/CD74 (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of FER (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of CHEK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of FES (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 27nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 34nMAssay Description:Inhibition of PTK2B (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 35nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 39nMAssay Description:Inhibition of CAMK2D (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 40nMAssay Description:Inhibition of CHEK1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 42nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetInsulin receptor-related protein(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 45nMAssay Description:Inhibition of INSRR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 47nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 48nMAssay Description:Inhibition of CAMK2G degradation (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 54nMAssay Description:Inhibition of LTK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 69nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein-tyrosine kinase 6(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 76nMAssay Description:Inhibition of BRK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 82nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 95nMAssay Description:Inhibition of C-MET (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664272BDBM50664272(CHEMBL6165880)
Affinity DataIC50: 161nMAssay Description:Inhibition of ROS1 G2032R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed