BDBM50664362 CHEMBL6148590

SMILES CCc1cc(=O)[nH]c(-n2nc(C)cc2N[C@@H](C)c2ccccc2)n1

InChI Key InChIKey=CAWNPHNPLIIGTM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50664362   

TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664362BDBM50664362(CHEMBL6148590)
Affinity DataIC50: 260nMAssay Description:Inhibition of adenylyl cyclase 1 (unknown origin) expressed in AC3/AC6 knockout HEK293 cells assessed as reduction in A23187-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664362BDBM50664362(CHEMBL6148590)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to serotonin 6 receptor (unknown origin) assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664362BDBM50664362(CHEMBL6148590)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to muscarinic M1 receptor (unknown origin) assessed as inhibition constant by radioligand displacement assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664362BDBM50664362(CHEMBL6148590)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of adenylyl cyclase 8 (unknown origin) expressed in AC3/AC6 knockout HEK293 cells assessed as reduction in A23187-stimulated cAMP accumula...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed