BDBM50664558 CHEMBL6168358

SMILES O=[N+]([O-])c1cccnc1Nc1cccc(C(F)(F)F)c1

InChI Key InChIKey=VHVORGQOUOILSR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50664558   

TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664558BDBM50664558(CHEMBL6168358)
Affinity DataIC50: 411nMAssay Description:Antagonist activity at Androgen receptor W742C mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664558BDBM50664558(CHEMBL6168358)
Affinity DataIC50: 659nMAssay Description:Antagonist activity at Androgen receptor F877L/T878A mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664558BDBM50664558(CHEMBL6168358)
Affinity DataIC50: 940nMAssay Description:Antagonist activity at DHT-induced Androgen receptor in human LNCaP cells expressing ARR2PB-eGFP incubated for 3 days by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664558BDBM50664558(CHEMBL6168358)
Affinity DataIC50: 1.52E+3nMAssay Description:Antagonist activity at Androgen receptor F877L mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664558BDBM50664558(CHEMBL6168358)
Affinity DataIC50: 8.53E+3nMAssay Description:Antagonist activity at LBP of Androgen receptor LBD (unknown origin) by PolarScreen competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed