BDBM50664559 CHEMBL6171672

SMILES O=[N+]([O-])c1ccc(Nc2cccc(C(F)(F)F)c2)nc1

InChI Key InChIKey=QYJNHEVAXNCZEE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50664559   

TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664559BDBM50664559(CHEMBL6171672)
Affinity DataIC50: 124nMAssay Description:Antagonist activity at Androgen receptor F877L mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664559BDBM50664559(CHEMBL6171672)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at DHT-induced Androgen receptor in human LNCaP cells expressing ARR2PB-eGFP incubated for 3 days by fluorescence based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664559BDBM50664559(CHEMBL6171672)
Affinity DataIC50: 429nMAssay Description:Antagonist activity at Androgen receptor F877L/T878A mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664559BDBM50664559(CHEMBL6171672)
Affinity DataIC50: 985nMAssay Description:Antagonist activity at Androgen receptor W742C mutant expressed in human PC-3 cells co-expressing ARR2PB-luc by Dual-Luciferase reporter assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664559BDBM50664559(CHEMBL6171672)
Affinity DataIC50: 4.79E+3nMAssay Description:Antagonist activity at LBP of Androgen receptor LBD (unknown origin) by PolarScreen competitive binding assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed