BDBM50664664 CHEMBL6172911

SMILES COc1ccc2c3cn(c2c1)CCCCC(=O)Nc1cc(c(OC)cc1N(C)CCN(C)C)Nc1nccc-3n1

InChI Key InChIKey=FLDIRPKQVDOGJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50664664   

TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664664BDBM50664664(CHEMBL6172911)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human EGFR T790M/L858R mutant (696 to end residues) extracted from baculovirus infect Sf21 insect cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664664BDBM50664664(CHEMBL6172911)
Affinity DataIC50: 332nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human EGFR 19del/T790M/C797S mutant (668 to end residues) extracted from Sf9 insect cells incubated f...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664664BDBM50664664(CHEMBL6172911)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant wildtype N-terminal GST-tagged human EGFR kinase domain (696 to end residues) extracted from baculovirus infect Sf21 insect...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed