BDBM50664669 CHEMBL6174285

SMILES COc1cc(N(C)CCN(C)C)c2cc1Nc1nccc(n1)Nc1ccc(cc1P(C)(C)=O)OCCCCC(=O)N2

InChI Key InChIKey=GYNICWGMHGMJAD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50664669   

TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664669BDBM50664669(CHEMBL6174285)
Affinity DataIC50: 111nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human EGFR T790M/L858R mutant (696 to end residues) extracted from baculovirus infect Sf21 insect cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664669BDBM50664669(CHEMBL6174285)
Affinity DataIC50: 113nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human EGFR 19del/T790M/C797S mutant (668 to end residues) extracted from Sf9 insect cells incubated f...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664669BDBM50664669(CHEMBL6174285)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant wildtype N-terminal GST-tagged human EGFR kinase domain (696 to end residues) extracted from baculovirus infect Sf21 insect...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed