BDBM50664811 CHEMBL6173708

SMILES CCn1ncc(Cl)c1-c1cc(F)cc(C(=O)NC[C@@H](N)C(=O)O)c1

InChI Key InChIKey=HGRWWKONPPQOBF-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50664811   

TargetGlutamate receptor ionotropic, NMDA 1(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664811BDBM50664811(CHEMBL6173708)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]-MDL105519 from GluN1 LBD (unknown origin) incubated for 30 mins by SPAMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664811BDBM50664811(CHEMBL6173708)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant human GluN1/2B expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664811BDBM50664811(CHEMBL6173708)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at recombinant human GluN1/2A expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2C(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664811BDBM50664811(CHEMBL6173708)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at recombinant human GluN1/2C expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664811BDBM50664811(CHEMBL6173708)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at recombinant human GluN1/2D expressed in Xenopus laevis oocytes in presence of glycine/glutamate by TEVC recording methodMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed