BDBM50664867 CHEMBL6172828

SMILES Cc1nc(C(F)(F)F)nc(-c2cc(NCCN(C)C)nc3[nH]ccc23)c1C

InChI Key InChIKey=VRGGERUGXSEQDF-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50664867   

TargetLymphocyte activation gene 3 protein(Homo sapiens)
Weill Cornell Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664867BDBM50664867(CHEMBL6172828)
Affinity DataKd:  2.94E+3nMAssay Description:Binding affinity to biotinylated His/Avi-tagged human LAG-3 (23 to 450 residues) lipophilic canyon binding site extracted from HEK293 cells assessed ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLymphocyte activation gene 3 protein(Homo sapiens)
Weill Cornell Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664867BDBM50664867(CHEMBL6172828)
Affinity DataKd:  5.83E+3nMAssay Description:Binding affinity to recombinant His-tagged human LAG3 lipophilic canyon binding site extracted from HEK293 cells assessed as dissociation constant in...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed