BDBM50664901 CHEMBL6171301

SMILES Clc1ccc(C(c2ccccc2)N2CCN(Cc3nnc(-c4cccc(Cl)c4)o3)CC2)cc1

InChI Key InChIKey=FWEFLHYONYEVFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50664901   

TargetProstaglandin G/H synthase 2(Sheep)
India Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664901BDBM50664901(CHEMBL6171301)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant ovine COX-2 using arachidonic acid as substrate in presence of hemin by TMPD reagent-based colorimetryMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
India Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664901BDBM50664901(CHEMBL6171301)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 10 min...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
India Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664901BDBM50664901(CHEMBL6171301)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate in presence of hemin by TMPD reagent-based colorimetryMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed